Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112608 | 1.00 | AHR (0.36) | AHRCYP19A1BACE1 | |
| SCHEMBL18112610 | 1.00 | AHR (0.36) | AHRCYP19A1BACE1 | |
| SCHEMBL18112609 | 0.89 | BACE1 (0.33) | AHRBACE1 | |
| SCHEMBL18112606 | 0.89 | BACE1 (0.33) | AHRBACE1 | |
| SCHEMBL18118831 | 0.88 | CYP19A1 (0.37) | CYP19A1BACE1 | |
| SCHEMBL18118651 | 0.88 | CYP19A1 (0.37) | CYP19A1BACE1 | |
| SCHEMBL18118826 | 0.86 | TUBB4A (0.34) | AHRBACE1 | |
| SCHEMBL18112603 | 0.84 | — | — | |
| SCHEMBL18112602 | 0.84 | — | — | |
| SCHEMBL18112611 | 0.84 | MAPT (0.38) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016155831-A1 | ISOXAZOLINE-STYRENE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016155831-A1 | ISOXAZOLINE-STYRENE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |