Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113258 | 0.88 | KMT2A (0.38) | KMT2AMEN1NPC1ALDH1A1TSHR | |
| SCHEMBL5665587 | 0.87 | KMT2A (0.48) | KMT2AMEN1NPC1ALDH1A1TSHR | |
| SCHEMBL18113248 | 0.85 | SMN1; SMN2 (0.44) | KMT2AMEN1ALDH1A1TSHRMAPT | |
| SCHEMBL18113108 | 0.84 | MAPT (0.43) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL18113227 | 0.83 | F2 (0.45) | KMT2ANPC1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16235996 | 0.81 | KMT2A (0.44) | KMT2AMEN1NPC1ALDH1A1TSHR | |
| SCHEMBL10633126 | 0.80 | TSHR (0.45) | KMT2AMEN1ALDH1A1TSHRMAPT | |
| SCHEMBL6574063 | 0.80 | TSHR (0.45) | KMT2AMEN1ALDH1A1TSHRMAPT | |
| SCHEMBL18113240 | 0.80 | KMT2A (0.53) | KMT2AMEN1NPC1ALDH1A1TSHR | |
| SCHEMBL10908312 | 0.78 | TSHR (0.43) | KMT2AMEN1NPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428870-B | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2019-06-14 | — | — | CN | disclosed |
| EP-3277736-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| CN-107428870-A | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2017-12-01 | — | — | CN | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |