Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113238 | 0.86 | TDP1 (0.43) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18113220 | 0.86 | TSHR (0.44) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18113251 | 0.84 | MAPT (0.40) | MAPTLMNASMN1; SMN2MAOBPLK1 | |
| SCHEMBL18113175 | 0.83 | LMNA (0.47) | MAPTLMNASMN1; SMN2PLK1ABCB1 | |
| SCHEMBL18113097 | 0.81 | TSHR (0.50) | MAPTLMNASMN1; SMN2PLK1MEN1 | |
| SCHEMBL18113107 | 0.79 | ELANE (0.41) | MAPTLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL16236047 | 0.76 | NPSR1 (0.36) | MAPTSMN1; SMN2PLK1ABCB1ESRRG | |
| SCHEMBL18113303 | 0.74 | TSHR (0.48) | MAPTLMNASMN1; SMN2PLK1ALDH1A1 | |
| SCHEMBL164673 | 0.72 | TSHR (0.52) | MAPTLMNASMN1; SMN2MAOBMEN1 | |
| SCHEMBL4625676 | 0.72 | TSHR (0.56) | MAPTLMNASMN1; SMN2MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277736-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |