SCHEMBL181187

SCHEMBL181187

CS(=O)(=O)CCCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5840333 0.88 ALDH1A1 (0.41)
SCHEMBL2210621 0.80
SCHEMBL777321 0.79 ALDH1A1 (0.52)
SCHEMBL3913999 0.79 ALDH1A1 (0.46)
SCHEMBL3294656 0.78
SCHEMBL26385508 0.77
SCHEMBL3406583 0.77
SCHEMBL9185106 0.76 ALDH1A1 (0.50)
SCHEMBL5461072 0.76 ALDH1A1 (0.50)
SCHEMBL7021059 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113444059-B Process for preparing 2- (methylsulfonyl) -oxirane and derivatives thereof 河北圣泰材料股份有限公司 2024-06-04 CN claimed
CN-113444059-A Process for the preparation of 2- (methylsulfonyl) -oxirane and derivatives thereof 石家庄圣泰化工有限公司 2021-09-28 CN claimed
US-12157751-B2 Process for the synthesis of oligomeric siloxane having sulfone moiety, and silicon-containing compounds having sulfone moiety MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2024-12-03 US disclosed
CN-113444059-B Process for preparing 2- (methylsulfonyl) -oxirane and derivatives thereof 河北圣泰材料股份有限公司 2024-06-04 CN disclosed
CN-117279925-A Method for synthesizing oligomeric siloxanes having sulfone moieties and silicon-containing compounds having sulfone moieties 迈图高新材料公司 2023-12-22 CN disclosed
US-20230348438-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2023-11-02 US disclosed
US-20230312617-A1 PROCESS FOR SYNTHESIS OF ORGANOSILICON COMPOUNDS FROM HALOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2023-10-05 US disclosed
US-20230312617-A1 PROCESS FOR SYNTHESIS OF ORGANOSILICON COMPOUNDS FROM HALOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2023-10-05 US disclosed
CN-116829565-A Method for synthesizing organosilicon compounds from halosilanes 迈图高新材料公司 2023-09-29 CN disclosed
US-20230246229-A1 ORGANIC SULFONATE ELECTROLYTE ADDITIVES FOR ZINC BATTERIES Octet Scientific, Inc. 2023-08-03 US disclosed
US-20220380391-A1 PROCESS FOR THE SYNTHESIS OF OLIGOMERIC SILOXANE HAVING SULFONE MOIETY, AND SILICON-CONTAINING COMPOUNDS HAVING SULFONE MOIETY MOMENTIVE PERFORMANCE MATERIALS INC. 2022-12-01 US disclosed
US-7544688-B2 Hetereoaryl nitrile derivatives NOVARTIS AG (CH) 2009-06-09 US disclosed
US-7544688-B2 Hetereoaryl nitrile derivatives NOVARTIS AG (CH) 2009-06-09 US disclosed
US-20090082457-A1 (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide; MEK kinase (mitogen-activated ERK-activating kinases, MAP kinase kinase); cancer, tumors, autoimmune disorders, ischemia, rheumatoid arthritis, multiple sclerosis, psoriasis, restenosis ANDREA BIOSCIENCES, INC. (US) 2009-03-26 US disclosed
WO-2009021965-A2 SUBSTITUTED QUINOLINE DERIVATIVES AS H1 RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2009-02-19 WO disclosed
US-7459414-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2008-12-02 US disclosed
US-7459414-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2008-12-02 US disclosed
US-20080221171-A1 Phenylaminopyridines BASILEA PHARMACEUTICA AG (CH) 2008-09-11 US disclosed
US-20080221171-A1 Phenylaminopyridines BASILEA PHARMACEUTICA AG (CH) 2008-09-11 US disclosed
US-20070197571-A1 Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of alzheimer' s disease MERCK SHARP & DOHME LLC 2007-08-23 US disclosed