SCHEMBL18119080

SCHEMBL18119080

c1ccc(-c2ccc(-c3ccc4c(c3)c3c5c(ccc3n4-c3ccc(-c4ccccc4)cc3)sc3ccccc35)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LIMK1 P53667 1/20 0.35
PIM3 Q86V86 1/20 0.34
JAK2 O60674 1/20 0.34
JAK3 P52333 1/20 0.34
GPR3 P46089 1/20 0.33
TSPO P30536 1/20 0.33
HDAC4 P56524 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
DUSP3 P51452 1/20 0.32
BLM P54132 1/20 0.32
PTPN5 P54829 1/20 0.32
PTPN11 Q06124 1/20 0.32
MCL1 Q07820 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18119151 1.00 KDM4E (0.37) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL18119066 1.00 KDM4E (0.37) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL18119149 1.00 KDM4E (0.37) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL24676208 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL18119061 0.97 L3MBTL1 (0.40) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL18119070 0.97 L3MBTL1 (0.40) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL19653561 0.96 L3MBTL1 (0.41) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL18119145 0.96 ATM (0.41) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL19652734 0.95 L3MBTL1 (0.43) KDM4EATML3MBTL1LIMK1PIM3
SCHEMBL23862278 0.95 L3MBTL1 (0.43) KDM4EATML3MBTL1LIMK1PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361372-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 US disclosed
US-20160293845-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160293845-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed