Demannose

Demannose

SCHEMBL1812

O=CC(O)C(O)C(O)C(O)CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TDP1 Q9NUW8 1/20 0.55
PDE4A P27815 1/20 0.46
AKR1B1 P15121 1/20 0.43
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
MPI P34949 1/20 0.35
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TOP1 P11387 1/20 0.33
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL1051912 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL14486320 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL15321015 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL525084 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL20956808 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL20500378 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL14958551 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL6529193 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL13947310 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Galactose SCHEMBL20818999 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 687487 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9974748-B2 Reduction of flake-like aggregation in nanoparticulate active agent compositions ALKERMES PHARMA IRELAND LIMITED (IE) 2018-05-22 US claimed
US-9974315-B2 Microencapsulated bacterial consortium for the degradation of gluten into sourdough and method for producing said sourdough GONZALEZ-DE LA TORRE, Javier (MX) 2018-05-22 US claimed
US-9974827-B2 Vasopressin formulations for use in treatment of hypotension PAR PHARMACEUTICAL, INC. (US) 2018-05-22 US claimed
US-20180133243-A1 METHOD AND COMPOSITION FOR CRUDE FORMULATIONS OF FORTIFIED SUGAR FOR GLYCEMIC CONTROL HAPPY SUGAR INC. 2018-05-17 US claimed
WO-2018089832-A1 DRUG-POLYMER PARTICLES WITH SUSTAINED RELEASE PROPERTIES UNIVERSITY OF WASHINGTON (US) 2018-05-17 WO claimed
WO-2018090004-A2 TUBERCULOSIS THERAPEUTIC COMPOUNDS AND METHODS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2018-05-17 WO claimed
WO-2018087361-A1 ORAL PHARMACEUTICAL COMPOSITIONS OF DEXKETOPROFEN AND ELETRIPTAN SANOVEL ILAC SANAYI VE TICARET A.S. (TR) 2018-05-17 WO claimed
US-20180133285-A1 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION PAR PHARMACEUTICAL, INC. 2018-05-17 US claimed
WO-2018085918-A1 NOVEL METHODS FOR CREATION OF SUB-MICRON BIOCARBON MATERIALS FROM BIOMASS AND THEIR FIELDS OF APPLICATION UNIVERSITY OF GUELPH (CA) 2018-05-17 WO claimed
US-20180134557-A1 STABILIZATION OF SODIUM DITHIONITE BY MEANS OF VARIOUS ADDITIVES BASF SE (DE) 2018-05-17 US claimed
US-3949102-A Frozen dessert product and process THE PROCTER & GAMBLE COMPANY (US) 1976-04-06 US claimed
US-3943171-A Method of producing acrylamide with a Raney copper catalyst NALCO CHEMICAL COMPANY (US) 1976-03-09 US claimed
US-3940509-A Semi-conducting materials and a method for the manufacture thereof UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-24 US claimed
US-3939041-A FROM DEXTROSE AND CROSSLINKED CELLS OF STREPTOMYCES CORNING GLASS WORKS (US) 1976-02-17 US claimed
US-3935070-A ENZYMATIC ISOMERIZATION CPC INTERNATIONAL INC. (US) 1976-01-27 US claimed
US-3934048-A Multifunctional sweetening composition GENERAL FOODS CORPORATION (US) 1976-01-20 US claimed
US-3933698-A Preparation of low friability rigid polyurethane foam OLIN CORPORATION (US) 1976-01-20 US claimed
US-3934053-A Candy filling with stabilized aroma CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) 1976-01-20 US claimed
US-3931148-A ALKALI SOLUBLE SURFACTANT BASF WYANDOTTE CORPORATION (US) 1976-01-06 US claimed
US-3931066-A HIGH RESILIENCE POLYURETHANE FOAM OLIN CORPORATION (US) 1976-01-06 US claimed