Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Atenolol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 known ✓ | P08588 | 4/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 1/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Atenolol SCHEMBL4362 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Esatenolol SCHEMBL4363 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL6509830 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL16165106 | 0.99 | ADRB2 (0.97) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL1155317 | 0.99 | ADRB2 (0.97) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL27238468 | 0.96 | ADRB2 (0.93) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL119797 | 0.96 | ADRB2 (0.93) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL27238436 | 0.95 | ADRB2 (0.90) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL2325992 | 0.94 | ADRB2 (0.88) | ADRB2ADRB1LMNATDP1ADRA1A | |
| Atenolol SCHEMBL5796984 | 0.94 | ADRB2 (0.88) | ADRB2ADRB1LMNATDP1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 42222 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026162-B1 | LID FOR USE IN A MASS SPECTROMETRY SYSTEM | DH TECHNOLOGIES DEV PTE LTD (SG) | 2026-05-20 | — | — | EP | claimed |
| WO-2026087423-A1 | METHOD FOR DETERMINING IMPROVED SETUP VALUES FOR A ROLL STAND FOR COLD ROLLING A STRIP | Primetals Technologies Austria GmbH (AT) | 2026-04-30 | — | — | WO | claimed |
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| EP-4699171-A1 | METHOD AND SYSTEM FOR PRODUCING A COMPOSITE CONSISTING OF AN ELECTRIC ARRESTER AND AT LEAST ONE ELECTRODE, COMPOSITE CONSISTING OF AN ELECTRIC ARRESTER AND AT LEAST ONE ELECTRODE, AND BATTERY CELL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2026-02-25 | — | — | EP | claimed |
| EP-4691556-A2 | HUMANIZED ANTI-ACTH ANTIBODIES AND USE THEREOF | H. Lundbeck A/S (DK) | 2026-02-11 | — | — | EP | claimed |
| US-20250382291-A1 | SUBSTITUTED PYRROLO[2,3-b]PYRIDINES FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS | UNIV COLUMBIA (US) | 2025-12-18 | — | — | US | claimed |
| US-20250302887-A1 | AMMONIA OXIDIZING MICROORGANISMS FOR THE REGULATION OF BLOOD PRESSURE | AOBIOME LLC (US) | 2025-10-02 | — | — | US | claimed |
| US-20250264469-A1 | METHODS FOR IMPROVING OUTCOMES FOR HEMATOPOIETIC CELL TRANSPLANT RECIPIENTS AT RISK FOR BRONCHIOLITIS OBLITERANS SYNDROME | CHILDREN'S HOSPITAL MEDICAL CENTER | 2025-08-21 | — | — | US | claimed |
| US-20250242092-A1 | SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS | SIO2 MEDICAL PRODUCTS INC (US) | 2025-07-31 | — | — | US | claimed |
| WO-2025101692-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF VASCULAR ANOMALIES | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-05-15 | — | — | WO | claimed |
| EP-0012212-A2 | Musical instrument programmable by means of perforated sheets | Geobra Brandstätter GmbH & Co. KG (DE) | 1980-06-25 | — | — | EP | claimed |
| EP-0009790-A1 | Device for indicating the drop below a predetermined filling level of a dosing material contained in a reservoir | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-16 | — | — | EP | claimed |
| WO-1980000525-A1 | CYLINDRE HEAD FOR THE TURNING UP OF FLEXIBLE MATERIAL,PARTICULARLY SYNTHETIC GUTS FOR THE PRODUCTION OF SAUSAGES | KOLLROSS G (DE) | 1980-04-03 | — | — | WO | claimed |
| EP-0009190-A1 | Curable composition useful for screen-printing, a cured coating comprising said composition and process for soldering printed circuit boards using said composition | International Business Machines Corporation (US) | 1980-04-02 | — | — | EP | claimed |
| EP-0008781-A1 | Radially expandable mandrel for longitudinally shirring tubular casings, especially artificial sausage casings | Kollross, Günter (DE) | 1980-03-19 | — | — | EP | claimed |
| EP-0008698-A1 | Impregnated electrical capacitor | SIEMENS AKTIENGESELLSCHAFT (DE) | 1980-03-19 | — | — | EP | claimed |
| WO-1980000133-A1 | METHOD AND INSTALLATION FOR MANUFACTURING MULTILAYER PIPES | MECANO BUNDY GMBH (DE) | 1980-02-07 | — | — | WO | claimed |
| EP-0007664-A1 | Process for coating and soldering workpieces with hard-metal alloys | METALLGESELLSCHAFT AG (DE) | 1980-02-06 | — | — | EP | claimed |
| EP-0007640-A1 | Bicycle frame | Firma Ernst Kleinebenne (DE) | 1980-02-06 | — | — | EP | claimed |
| EP-0006624-A2 | Method for manufacturing ultrasonic transducers | SIEMENS AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | claimed |