Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HPGDS | O60760 | 2/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | MELK | Q14680 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279990 | 0.89 | RAB9A (0.75) | RAB9APOLBHPGDSALDH1A1CYP1A2 | |
| SCHEMBL17279793 | 0.83 | RAB9A (0.72) | RAB9APOLBHPGDSALDH1A1CYP1A2 | |
| SCHEMBL15006259 | 0.82 | RAB9A (0.70) | RAB9APOLBHPGDSALOX15L3MBTL1 | |
| SCHEMBL21466398 | 0.81 | RAB9A (0.58) | RAB9APOLBHPGDSCYP11B1CYP11B2 | |
| SCHEMBL18120003 | 0.81 | RAB9A (0.58) | RAB9APOLBHPGDSCYP11B1CYP11B2 | |
| SCHEMBL19199562 | 0.81 | RAB9A (0.58) | RAB9APOLBHPGDSCYP11B1CYP11B2 | |
| SCHEMBL7395528 | 0.80 | RAB9A (0.79) | RAB9APOLBHPGDSALOX15L3MBTL1 | |
| SCHEMBL1230353 | 0.79 | RAB9A (1.00) | RAB9APOLBHPGDSALDH1A1CYP1A2 | |
| SCHEMBL10358677 | 0.79 | RAB9A (0.70) | RAB9APOLBHPGDSALDH1A1ALOX15 | |
| SCHEMBL17279811 | 0.78 | RAB9A (0.64) | RAB9APOLBHPGDSALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136403-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |
| US-20160289212-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2016-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289212-A1 | HEPATITIS B ANTIVIRAL AGENTS | ZC3HAV1, HAVCR2, SLC10A1 | RAB9A 1138/4885POLB 663/4885HPGDS 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.