Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402800 | 0.84 | MEN1 (0.51) | MEN1KMT2AGAATDP1FOLH1 | |
| SCHEMBL180974 | 0.82 | HDAC3 (0.48) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL17254414 | 0.78 | MEN1 (0.55) | MEN1KMT2AGAATDP1FOLH1 | |
| SCHEMBL3474501 | 0.78 | TDP1 (0.47) | HDAC8CYP3A4TDP1HPGDHTT | |
| SCHEMBL22402873 | 0.78 | TDP1 (0.47) | HDAC8CYP3A4TDP1HPGDHTT | |
| SCHEMBL7207224 | 0.77 | TDP1 (0.69) | MEN1KMT2AGAAHDAC8CYP3A4 | |
| SCHEMBL31307530 | 0.76 | KMT2A (0.43) | MEN1KMT2AGAATDP1 | |
| SCHEMBL18466946 | 0.76 | NR2F2 (0.40) | MEN1KMT2AGAAHDAC1HDAC8 | |
| SCHEMBL20122339 | 0.76 | MEN1 (0.55) | MEN1KMT2AGAAHDAC1HDAC8 | |
| SCHEMBL18145560 | 0.76 | FOLH1 (0.46) | MEN1KMT2AGAATDP1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942351-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |