SCHEMBL180974

SCHEMBL180974

O=C(CI)NCCCCCC(=O)NCCCCC(C(=O)O)N1C(=O)CCC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 5/20 0.48
HDAC4 P56524 5/20 0.48
HDAC1 Q13547 5/20 0.48
HDAC7 Q8WUI4 5/20 0.48
HDAC2 Q92769 5/20 0.48
HDAC10 Q969S8 5/20 0.48
HDAC11 Q96DB2 5/20 0.48
HDAC8 Q9BY41 5/20 0.48
HDAC6 Q9UBN7 5/20 0.48
HDAC9 Q9UKV0 5/20 0.48
HDAC5 Q9UQL6 5/20 0.48
SMN1; SMN2 Q16637 2/20 0.40
FOLH1 Q04609 2/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 2/20 0.37
PKM P14618 1/20 0.37
ALB P02768 4/20 0.37
TDP1 Q9NUW8 1/20 0.36
NAMPT P43490 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181008 0.94 HDAC3 (0.42) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL18123719 0.82 MEN1 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL44176 0.79 HDAC3 (0.42) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL15069739 0.78 FOLH1 (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL846234 0.77 ALDH1A1 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL17821007 0.77 ALDH1A1 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL25305424 0.76 TDP1 (0.70) FOLH1PKMTDP1
SCHEMBL20537346 0.76 TDP1 (0.70) FOLH1PKMTDP1
SCHEMBL28653646 0.76 TDP1 (0.70) FOLH1PKMTDP1
SCHEMBL30773222 0.75 ALDH1A1 (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250352663-A1 Nanoclusters Functionalized with Adenosine Triphosphate or an Analogue and Their Use UNIV LELAND STANFORD JUNIOR (US) 2025-11-20 US disclosed
EP-4486394-A1 FUNCTIONALIZED NANOCLUSTERS AND THEIR USE IN TREATING BACTERIAL INFECTIONS The Board Of Trustees Of The Leland Stanford Junior University (US) 2025-01-08 EP disclosed
US-11998615-B2 Functionalized nanoparticles and their use in treating bacterial infections THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-06-04 US disclosed
US-20240148882-A1 METHODS OF TREATING AN OCULAR DISEASE OR DISORDER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-05-09 US disclosed
WO-2024044636-A2 NANOCLUSTERS FUNCTIONALIZED WITH ADENOSINE TRIPHOSPHATE OR AN ANALOGUE AND THEIR USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-02-29 WO disclosed
WO-2023164224-A1 FUNCTIONALIZED NANOCLUSTERS AND THEIR USE IN TREATING BACTERIAL INFECTIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-08-31 WO disclosed
US-11723982-B2 Methods of treating an ocular disease or disorder THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-15 US disclosed
US-20230149561-A1 Functionalized Nanoparticles and Their Use in Treating Bacterial Infections THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-05-18 US disclosed
US-20220339293-A1 FUNCTIONALIZED NANOPARTICLES AND THEIR USE IN TREATING BACTERIAL INFECTIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2022-10-27 US disclosed
US-20220265763-A1 POLYPEPTIDE-POLYMER CONJUGATES AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2022-08-25 US disclosed
US-20040115168-A1 Interferon beta: remodeling and glycoconjugation of interferon beta NEOSE TECHNOLOGIES, INC. 2004-06-17 US disclosed
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha NEOSE TECHNOLOGIES, INC. 2004-04-29 US disclosed
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF NEOSE TECHNOLOGIES, INC. 2004-04-22 US disclosed
WO-2004033651-A2 ERYTHROPOIETIN: REMODELING AND GLYCOCONJUGATION OF ERYTHROPOIETIN NEOSE TECHNOLOGIES, INC. (US) 2004-04-22 WO disclosed
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods NEOSE TECHNOLOGIES, INC. 2004-04-01 US disclosed
US-20040043446-A1 Alpha galalctosidase a: remodeling and glycoconjugation of alpha galactosidase A NEOSE TECHNOLOGIES, INC. 2004-03-04 US disclosed
US-20040001892-A1 Tunable, semi-interpenetrating polymer networks (sIPNS) for medicine and biotechnology THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-01-01 US disclosed
WO-2003031464-A2 REMODELING AND GLYCOCONJUGATION OF PEPTIDES NEOSE TECHNOLOGIES, INC. (US) 2003-04-17 WO disclosed
EP-1218413-A2 ENGINEERING ANTIBODIES THAT BIND IRREVERSIBLY The Regents of the University of California (US) 2002-07-03 EP disclosed
WO-2001022922-A2 ENGINEERING ANTIBODIES THAT BIND IRREVERSIBLY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF CSF3R, CSF1R, GMFG HDAC3 1432/4885HDAC4 1334/4885HDAC1 927/4885
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha IFNG, IFNAR1, IRF3 HDAC3 1056/4885HDAC4 908/4885HDAC1 1364/4885
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods PTMS, ANPEP, SMURF1 HDAC3 1781/4885HDAC4 2481/4885HDAC1 2105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.