Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245223 | 0.97 | ADH5 (0.51) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL243144 | 0.96 | ADH5 (0.51) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL1976466 | 0.84 | ADH5 (0.52) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL244392 | 0.84 | MAPT (0.52) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL239456 | 0.84 | ADH5 (0.53) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL243613 | 0.83 | ADH5 (0.54) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL248186 | 0.82 | ADH5 (0.55) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL243477 | 0.82 | ADH5 (0.56) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL242620 | 0.80 | MAPT (0.59) | ADH5CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL242957 | 0.78 | ADH5 (0.62) | ADH5CYP2C19MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318006-B1 | NOVEL PYRROLE INHIBITORS OF S-NITROSOGLUTATHIONE REDUCTASE AS THERAPEUTIC AGENTS | NIVALIS THERAPEUTICS INC (US) | 2016-10-12 | — | — | EP | claimed |