SCHEMBL1812464

SCHEMBL1812464

CC(Cc1ccc(Cl)cc1)NC(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.57
CNR2 P34972 1/20 0.57
ACACB O00763 1/20 0.55
FPR2 P25090 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
ITGB1 P05556 10/20 0.51
ITGA4 P13612 10/20 0.51
ITGA2 P17301 1/20 0.50
ITGB7 P26010 1/20 0.50
PSMB5 P28074 1/20 0.48
LMNA P02545 1/20 0.46
UTS2R Q9UKP6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1816209 0.84 ACACB (0.53) ACACBFPR2NPC1RAB9AITGB1
SCHEMBL1811166 0.82 SMN1; SMN2 (0.55) CNR1CNR2ACACBFPR2NPC1
SCHEMBL18607965 0.82 ITGB1 (0.76) ITGB1ITGA4ITGA2ITGB7
SCHEMBL20387787 0.80 PKM (0.54) RAB9AITGB1ITGA4PSMB5
SCHEMBL19541999 0.78 HPGD (0.45) CNR1CNR2ITGB1ITGA4ITGA2
SCHEMBL12654827 0.78 ACACB (0.50) CNR1CNR2ACACBFPR2NPC1
SCHEMBL9893002 0.78 ACACB (0.82) ACACB
SCHEMBL13452696 0.78 NPC1 (0.59) NPC1RAB9AITGB1ITGA4ITGA2
SCHEMBL12621261 0.77 UTS2R (0.54) ACACBFPR2NPC1RAB9AUTS2R
SCHEMBL19541874 0.77 NPC1 (0.54) NPC1RAB9AITGB1ITGA4PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960350-B1 NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-08-19 EP disclosed
US-8314269-B2 N-(1-methyl-2phenylethyl)benzamide derivatives BAYER CROPSCIENCE AG (DE) 2012-11-20 US disclosed
US-20110237678-A1 N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-09-29 US disclosed
US-7951973-B2 N-(1-methyl-2Phenylethyl)benzamide derivatives BAYER CROPSCIENCE AG (DE) 2011-05-31 US disclosed
US-7951973-B2 N-(1-methyl-2Phenylethyl)benzamide derivatives BAYER CROPSCIENCE AG (DE) 2011-05-31 US disclosed
US-20090156682-A1 N-(1-Methyl-2Phenylethyl)Benzamide Derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2009-06-18 US disclosed
EP-1960350-A1 NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2008-08-27 EP disclosed
WO-2007060162-A1 NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2007-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156682-A1 N-(1-Methyl-2Phenylethyl)Benzamide Derivatives CYP51A1, CYP1A2, CYP1A1 CNR1 2980/4885CNR2 3023/4885ACACB 2344/4885
US-20110237678-A1 N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES CYP51A1, CYP1A2, CYP1A1 CNR1 3065/4885CNR2 3080/4885ACACB 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.