Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.97 |
| ▸ | POLB | P06746 | 1/20 | 0.97 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.86 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.86 |
| ▸ | LMNA | P02545 | 3/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.86 |
| ▸ | TSHR | P16473 | 3/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.86 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.86 |
| ▸ | THRB | P10828 | 1/20 | 0.86 |
| ▸ | HTT | P42858 | 1/20 | 0.86 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.86 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caramiphen SCHEMBL1374820 | 0.99 | ALDH1A1 (1.00) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Caramiphen SCHEMBL10898559 | 0.99 | PRCP (0.97) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Hydrochloric Acid SCHEMBL7383119 | 0.97 | ALDH1A1 (0.97) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| SCHEMBL8107029 | 0.97 | PRCP (0.95) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Hydrochloric Acid SCHEMBL8107092 | 0.96 | ALDH1A1 (0.95) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Hydrochloric Acid SCHEMBL7384475 | 0.93 | ALDH1A1 (0.90) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Caramiphen SCHEMBL8735818 | 0.93 | ALDH1A1 (0.88) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Hydrochloric Acid SCHEMBL8523290 | 0.92 | ALDH1A1 (0.88) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Carbetapentane SCHEMBL67879 | 0.92 | CHRM2 (1.00) | PRCPSIGMAR1ALDH1A1POLBCHRM2 | |
| Carbetapentane SCHEMBL15516338 | 0.92 | CHRM2 (1.00) | PRCPSIGMAR1ALDH1A1POLBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4078 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986146-A | Preparation method and detection method of citric acid pentovirine impurity | 河南优凯制药有限公司 | 2024-05-07 | — | — | CN | claimed |
| US-11744829-B2 | Methods for treating neurological conditions and exposure to nerve agents | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2023-09-05 | — | — | US | claimed |
| US-11419938-B2 | Phenylephrine-containing liquid formulations | GLAXOSMITHKLINE CONSUMER HEALTHCARE HOLDINGS LLC (US) | 2022-08-23 | — | — | US | claimed |
| US-20210393615-A1 | METHODS FOR TREATING NEUROLOGICAL CONDITIONS AND EXPOSURE TO NERVE AGENTS | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2021-12-23 | — | — | US | claimed |
| US-11045462-B2 | Methods for treating neurological conditions and exposure to nerve agents | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2021-06-29 | — | — | US | claimed |
| US-20190321351-A1 | METHODS FOR TREATING NEUROLOGICAL CONDITIONS AND EXPOSURE TO NERVE AGENTS | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2019-10-24 | — | — | US | claimed |
| US-20190209688-A1 | Phenylephrine-Containing Liquid Formulations | WYETH LLC (US) | 2019-07-11 | — | — | US | claimed |
| CN-105732991-B | polymer and pharmaceutical composition comprising the same | 财团法人工业技术研究院 | 2019-04-23 | — | — | CN | claimed |
| EP-1986606-B1 | PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS | WYETH LLC (US) | 2019-04-10 | — | — | EP | claimed |
| WO-2017218344-A1 | METHODS FOR TREATING NEUROLOGICAL CONDITIONS AND EXPOSURE TO NERVE AGENTS | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2017-12-21 | — | — | WO | claimed |
| US-4906638-A | Dextromethorphan potentiator for anticonvulsant composition and method | NOVA PHARMACEUTICAL CORPORATION (US) | 1990-03-06 | — | — | US | claimed |
| WO-1989005641-A1 | DEXTROMETHORPHAN POTENTIATOR FOR ANTICONVULSANT COMPOSITION AND METHOD | PONTECORVO MICHAEL J (US) | 1989-06-29 | — | — | WO | claimed |
| EP-0233932-A4 | ANTICONVULSANT COMPOSITIONS AND METHOD. | UNIV NEW YORK (US) | 1988-04-26 | — | — | EP | claimed |
| US-4694010-A | DIPHENYLHYDANTOIN AS POTENTIATOR FOR DEXTROMETHORPHAN AS ANTIEPILEPTIC | NEW YORK UNIVERSITY (US) | 1987-09-15 | — | — | US | claimed |
| EP-0233932-A1 | ANTICONVULSANT COMPOSITIONS AND METHOD | NEW YORK UNIVERSITY (US) | 1987-09-02 | — | — | EP | claimed |
| WO-1987001036-A1 | ANTICONVULSANT COMPOSITIONS AND METHOD | NEW YORK UNIVERSITY (US) | 1987-02-26 | — | — | WO | claimed |
| EP-0180597-A1 | COUGH/COLD MIXTURES COMPRISING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS. | SUNSHINE ABRAHAM (US) | 1986-05-14 | — | — | EP | claimed |
| WO-1985004589-A1 | COUGH/COLD MIXTURES COMPRISING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | SUNSHINE ABRAHAM | 1985-10-24 | — | — | WO | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| US-4175119-A | Composition and method to prevent accidental and intentional overdosage with psychoactive drugs | PORTER GARRY L | 1979-11-20 | — | — | US | claimed |