⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976596 | 0.82 | — | — | |
| SCHEMBL30603171 | 0.76 | — | — | |
| SCHEMBL5203421 | 0.76 | HTT (0.45) | — | |
| SCHEMBL1476199 | 0.76 | — | — | |
| SCHEMBL248926 | 0.76 | — | — | |
| SCHEMBL931245 | 0.73 | GRM5 (0.51) | — | |
| SCHEMBL8486570 | 0.73 | GRM5 (0.47) | — | |
| SCHEMBL4974 | 0.73 | — | — | |
| SCHEMBL14843947 | 0.71 | — | — | |
| SCHEMBL1040544 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | claimed |
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | MONASH UNIVERSITY (AU) | 2022-01-18 | — | — | US | claimed |
| US-20180282374-A1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | MONASH UNIVERSITY (AU) | 2018-10-04 | — | — | US | claimed |
| EP-2056897-B1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES B V (NL) | 2009-12-30 | — | — | EP | claimed |
| US-20090258053-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEEVICES BV (NL) | 2009-10-15 | — | — | US | claimed |
| EP-2056897-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | Blue Medical Devices B.V. (NL) | 2009-05-13 | — | — | EP | claimed |
| US-20080050413-A1 | Medical stent provided with a combination of melatonin and paclitaxel | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | US | claimed |
| WO-2008023038-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | WO | claimed |
| US-6388081-B1 | 4-substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries | LION BIOSCIENCE AG (DE) | 2002-05-14 | — | — | US | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| EP-0977989-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0271059-B1 | 2-Methylthiomethyl-dihydropyridines, a process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-10-20 | — | — | EP | claimed |
| EP-0251732-B1 | PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1993-04-28 | — | — | EP | claimed |
| US-4971984-A | Cardiovascular disorders, hypotensive agints | BEEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1990-11-20 | — | — | US | claimed |
| US-4870179-A | Process for preparing lysergol derivatives | INVERNI DELLA BEFFA SPA (IT) | 1989-09-26 | — | — | US | claimed |
| EP-0171988-B1 | A PROCESS FOR PREPARING LYSERGOL DERIVATIVES | INVERNI DELLA BEFFA S.P.A. (IT) | 1989-06-21 | — | — | EP | claimed |
| US-4816587-A | Process for the preparation of 2-halogenated ergoline derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-03-28 | — | — | US | claimed |
| EP-0251732-A2 | Process for the preparation of 2-halogenated ergoline derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1988-01-07 | — | — | EP | claimed |
| EP-0171988-A2 | A process for preparing lysergol derivatives | INVERNI DELLA BEFFA S.P.A. (IT) | 1986-02-19 | — | — | EP | claimed |