SCHEMBL8976596

SCHEMBL8976596

O=[C]c1cncc([C]=O)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14843947 0.82
SCHEMBL1521247 0.82
SCHEMBL11725842 0.77 VCAM1 (0.45)
SCHEMBL20448751 0.77 CYP11B2 (0.38)
SCHEMBL8922148 0.77 HCAR2 (0.53)
SCHEMBL356245 0.75
SCHEMBL2321463 0.72 HDAC1 (0.41)
SCHEMBL2320062 0.72 GRM5 (0.50)
SCHEMBL936524 0.69 CYP11B1 (0.47)
SCHEMBL28184881 0.67 CYP11B1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561782-B1 PROCESS FOR PREPARATION OF AROMATIC THIOL ESTERS ROHM & HAAS (US) 1996-04-17 EP claimed
US-3931142-A Heterocyclic containing disazo compounds CIBA-GEIGY AG (CH) 1976-01-06 US claimed
US-3931142-A Heterocyclic containing disazo compounds CIBA-GEIGY AG (CH) 1976-01-06 US disclosed