Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580330 | 0.74 | MKNK2 (0.46) | MKNK2FDPSCYP1A2CYP3A4TSHR | |
| SCHEMBL2417987 | 0.73 | MKNK2 (0.40) | MKNK2FDPSCYP1A2CYP3A4TSHR | |
| SCHEMBL3697841 | 0.72 | MKNK2 (0.49) | MKNK2FDPSCYP1A2CYP3A4TSHR | |
| SCHEMBL26126509 | 0.72 | BCHE (0.42) | MKNK2CYP1A2CYP3A4TSHRCLK4 | |
| SCHEMBL20520353 | 0.70 | MKNK2 (0.42) | MKNK2FDPSCYP1A2CYP3A4TSHR | |
| SCHEMBL28189820 | 0.70 | MKNK2 (0.42) | MKNK2FDPSCYP1A2CYP3A4TSHR | |
| SCHEMBL793846 | 0.70 | MKNK2 (0.48) | MKNK2FDPSCYP1A2CYP3A4TSHR | |
| SCHEMBL27715441 | 0.69 | MKNK2 (0.41) | MKNK2FDPSCYP1A2CYP3A4TSHR | |
| SCHEMBL3027720 | 0.69 | PI4KA (0.57) | MKNK2CYP1A2CYP3A4TSHRFGFR1 | |
| SCHEMBL1803928 | 0.68 | HTT (0.55) | MKNK2FGFR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117844810-A | Promoter for improving expression level of glycinamide nucleotide synthetase and application thereof | 华南理工大学 | 2024-04-09 | — | — | CN | disclosed |
| EP-2493895-A1 | N-CONTAINING HETEROARYL DERIVATIVES AS JAK3 KINASE INHIBITORS | Palau Pharma, S.A. (ES) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051452-A1 | N-CONTAINING HETEROARYL DERIVATIVES AS JAK3 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2011-05-05 | — | — | WO | disclosed |
| US-5656742-A | Ring-opened purine compounds for labeling polynucleotides | UNIVERSITY OF MIAMI (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0625985-B1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES | UNIV MIAMI (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5593829-A | Method for labeling DNA by ring-opening of purine bases | UNIVERSITY OF MIAMI (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0625985-A1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES. | UNIV MIAMI (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993011146-A1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES | UNIVERSITY OF MIAMI (US) | 1993-06-10 | — | — | WO | disclosed |