Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 2/20 | 0.48 |
| ▸ | RORC | P51449 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582086 | 0.89 | SPPL2A (0.48) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL6872886 | 0.89 | SPPL2A (0.49) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL611342 | 0.89 | SPPL2A (0.47) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL28778215 | 0.89 | SPPL2A (0.47) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL8222120 | 0.88 | SPPL2A (0.44) | SPPL2AALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL13964089 | 0.86 | SPPL2A (0.53) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL1813919 | 0.86 | SPPL2A (0.53) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL469706 | 0.84 | SPPL2A (0.68) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL1234685 | 0.84 | SPPL2A (0.68) | SPPL2ARORCALDH1A1KMT2AMAPK1 | |
| SCHEMBL1668736 | 0.84 | SPPL2A (0.68) | SPPL2ARORCALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061590-A1 | NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2011-05-26 | — | — | WO | disclosed |