SCHEMBL18134305

SCHEMBL18134305

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5cccc(-c6cccc(-c7ccccc7-c7ccc8ccccc8c7)c6)c5)c4)c3)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
ALDH1A1 P00352 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 3/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HSD17B1 P14061 1/20 0.49
HSD17B2 P37059 1/20 0.49
GSTP1 P09211 1/20 0.47
CYP17A1 P05093 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
ADORA2A P29274 2/20 0.45
ADORA1 P30542 2/20 0.45
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27252840 1.00 MEN1 (0.50) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL17720927 0.98 MEN1 (0.49) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL27252699 0.98 MEN1 (0.49) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL24377036 0.97 HSD17B1 (0.49) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL24377071 0.97 HSD17B1 (0.49) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL27252877 0.97 MEN1 (0.50) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL24353199 0.95 MEN1 (0.46) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL27252374 0.95 MEN1 (0.49) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL27257527 0.95 MEN1 (0.54) MEN1ALDH1A1KMT2AKDM4ETP53
SCHEMBL26154429 0.95 MEN1 (0.54) MEN1ALDH1A1KMT2AKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177441-B2 Organic compound, composition, organic optoelectronic device, and display device SAMSUNG SDI CO., LTD. (KR) 2021-11-16 US disclosed
US-10355224-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, and organic optoelectronic device and display device comprising same SAMSUNG SDI CO., LTD. (KR) 2019-07-16 US disclosed
US-20170346020-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING SAME SAMSUNG SDI CO., LTD. (KR) 2017-11-30 US disclosed
US-20170346020-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING SAME SAMSUNG SDI CO., LTD. (KR) 2017-11-30 US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 US disclosed
US-20170098778-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-06 US disclosed
US-20170098778-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-06 US disclosed
US-20170092873-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-03-30 US disclosed
US-20170092873-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-03-30 US disclosed
US-20170084845-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-03-23 US disclosed
US-20170084845-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-03-23 US disclosed
US-20160301012-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-10-13 US disclosed
US-20160301012-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170092873-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OCIAD1 MEN1 2474/4885ALDH1A1 149/4885KMT2A 4494/4885
US-20170346020-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING SAME OR10J3, OXER1, OCIAD1 MEN1 3024/4885ALDH1A1 35/4885KMT2A 3969/4885
US-20160301012-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 MEN1 568/4885ALDH1A1 230/4885KMT2A 3434/4885
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE OCIAD2, OCIAD1, OR10J3 MEN1 2593/4885ALDH1A1 105/4885KMT2A 3837/4885
US-20170098778-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OCIAD1 MEN1 3172/4885ALDH1A1 128/4885KMT2A 4483/4885
US-20170084845-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, OR10J3 MEN1 3632/4885ALDH1A1 48/4885KMT2A 3917/4885
US-10355224-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, and organic optoelectronic device and display device comprising same OR10J3, OXER1, OCIAD1 MEN1 3024/4885ALDH1A1 35/4885KMT2A 3969/4885
US-11177441-B2 Organic compound, composition, organic optoelectronic device, and display device OXER1, OR10J3, OR51E2 MEN1 568/4885ALDH1A1 230/4885KMT2A 3434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.