⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965875 | 0.85 | GRM2 (0.40) | — | |
| SCHEMBL20524196 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL22134255 | 0.75 | — | — | |
| SCHEMBL8442812 | 0.73 | — | — | |
| SCHEMBL25660688 | 0.73 | — | — | |
| SCHEMBL8442483 | 0.73 | — | — | |
| SCHEMBL25662364 | 0.73 | — | — | |
| SCHEMBL12557600 | 0.71 | — | — | |
| SCHEMBL13472248 | 0.71 | — | — | |
| SCHEMBL5552599 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324911-A1 | THERAPEUTIC PEPTIDES | COHBAR, INC. | 2022-10-13 | — | — | US | disclosed |
| EP-2401257-A1 | ENZYME INHIBITORS | Chroma Therapeutics Ltd. (GB) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097586-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2010-09-02 | — | — | WO | disclosed |