SCHEMBL18138374

SCHEMBL18138374

CC(=O)C(=O)OC(C)(CC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
ALDH1A1 P00352 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
FFAR1 O14842 1/20 0.34
CPT2 P23786 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1131245 0.84 GAA (0.32) CYP2C19HIF1ACYP2D6TSHRGAA
SCHEMBL543869 0.84 TSHR (0.40) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL18233428 0.79 CYP2C19 (0.39) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL416276 0.78 CYP2C19 (0.50) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL3713463 0.78 CYP2C19 (0.50) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL4628158 0.78 CYP2C19 (0.50) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL1270962 0.77 CYP2C19 (0.39) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL259010 0.73 HMGCR (0.43) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL29203945 0.73 TSHR (0.41) CYP2C19HIF1ACYP2D6TSHRHMGCR
SCHEMBL7558348 0.72 TSHR (0.40) CYP2C19HIF1ACYP2D6TSHRHMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081639-A1 Acyl amino acid production Evonik Degussa GmbH (DE) 2016-10-19 EP disclosed