Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628164 | 0.74 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL19469695 | 0.74 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL18138374 | 0.73 | CYP2C19 (0.43) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL6040141 | 0.73 | ALDH1A1 (0.56) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL1357615 | 0.73 | HMGCR (0.60) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL61203 | 0.73 | HMGCR (0.60) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL29816178 | 0.73 | HMGCR (0.60) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL346880 | 0.73 | HMGCR (0.60) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL29203945 | 0.72 | TSHR (0.41) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL3713463 | 0.72 | CYP2C19 (0.50) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9267158-B2 | Biological production of multi-carbon compounds from methane | INTREXON CORPORATION (US) | 2016-02-23 | — | — | US | disclosed |
| US-8133704-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2012-03-13 | — | — | US | disclosed |
| EP-2366026-A2 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM ALPHA KETOACIDS | Celexion, Llc (US) | 2011-09-21 | — | — | EP | disclosed |
| US-20110171696-A1 | Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks | CELEXION, LLC (US) | 2011-07-14 | — | — | US | disclosed |