SCHEMBL181389

SCHEMBL181389

N#CCCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5146991 1.00
Phosphine SCHEMBL23362773 0.96
Hydrochloric Acid SCHEMBL10350718 0.96
Hydrochloric Acid SCHEMBL10350716 0.93
SCHEMBL9827988 0.87 TSHR (0.75)
SCHEMBL7505017 0.82 CYP3A4 (0.67)
Thiosulfuric Acid SCHEMBL11034917 0.78 CYP3A4 (0.60)
SCHEMBL435492 0.77
SCHEMBL851045 0.74
SCHEMBL7454479 0.72 TSHR (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1044 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120060221-A Modification method for improving substrate specificity and catalytic activity of aliphatic nitrilase and modified mutant 江南大学 2025-05-30 CN claimed
CN-115232138-B Huperzine A intermediate and nontoxic synthesis process of raw materials thereof 杭州师范大学 2024-01-30 CN claimed
EP-4309002-A1 RECORDING A LATENT HOLOGRAPHIC GRATING AND AMPLIFICATION OF ITS DYNAMIC RANGE META PLATFORMS TECHNOLOGIES, LLC (US) 2024-01-24 EP claimed
CN-117015745-A Recording a latent holographic grating and magnifying its dynamic range 元平台技术有限公司 2023-11-07 CN claimed
CN-114477212-B Organic functional group modified SBA molecular sieve and preparation method and application thereof 中国石油化工股份有限公司 2023-09-08 CN claimed
CN-114477202-B Organic functional group modified MCM molecular sieve and preparation method and application thereof 中国石油化工股份有限公司 2023-07-21 CN claimed
CN-116082166-A Preparation method of rasagiline mesylate 上海复旦复华药业有限公司 2023-05-09 CN claimed
CN-110655622-B Method for preparing polymer brush micropattern based on maskless lithography system 华东理工大学 2023-05-05 CN claimed
US-20230081986-A1 METHOD AND REAGENTS TO IMPROVE NONANIMAL OCULAR TOXICITY TESTS LEBRUN LABS LLC (US) 2023-03-16 US claimed
CN-217888009-U Production system of bulk drug intermediate famotidine side chain product 无棣融川医药化工科技有限公司 2022-11-25 CN claimed
US-4931391-A STABILIZING SOLUTIONS WITH NITRILES, AMIDES, CARBOXYLIC ACIDS OR SALTS MITSUBISHI RAYON KABUSHIKI KAISHA (JP) 1990-06-05 US claimed
US-4900672-A MIXING WITH NITRILE, AMIDE, ORGANIC ACID OR SALT STABILIZER NITTO KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-02-13 US claimed
EP-0325014-A1 Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine ICI AMERICAS INC. (US) 1989-07-26 EP claimed
EP-0149634-B1 PROCESS FOR THE DEFINITE CROSS-LINKING OF DOUBLE HELIX DNA FRAGMENTS BY MEANS OF A LINKAGE DNA AS WELL AS OLIGONUCLEOTIDES USED AS LINKAGE DNA BIOSYNTECH Biochemische Synthesetechnik GmbH (DE) 1988-10-12 EP claimed
US-4734502-A Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine ICI AMERICAS INC. (US) 1988-03-29 US claimed
EP-0128736-B1 NOVEL 2-GUANIDINOTHIAZOLINE COMPOUNDS, THEIR PREPARATION, AND THEIR USE AS INTERMEDIATES YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-02-25 EP claimed
US-4609737-A DIHALOACETONE AND AMIDINOTHIOUREA YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-09-02 US claimed
EP-0128736-A1 Novel 2-guanidinothiazoline compounds, their preparation, and their use as intermediates YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1984-12-19 EP claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
US-4028142-A ON IRON, BORON, SILICON ANDOR GROUP 4B TO 6B METALS BY DECOMPOSITION TO PRODUCE DIFFUSION LAYERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US claimed