Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.47 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL18141522 | 1.00 | DNM1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL18139039 | 1.00 | DNM1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL18139921 | 1.00 | DNM1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL18140655 | 1.00 | DNM1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL18140552 | 1.00 | DNM1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL18141128 | 1.00 | DNM1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL18139973 | 1.00 | DNM1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL4307685 | 0.98 | DNM1 (0.63) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8871547 | 0.98 | DNM1 (0.63) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18140342 | 0.97 | MEN1 (0.64) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428194-B2 | Modified acrylic resin cured product, and laminate thereof, and production methods therefor | MITSUI CHEMICALS, INC. (JP) | 2019-10-01 | — | — | US | disclosed |
| EP-3263635-B1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | MITSUI CHEMICALS INC (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-20180163056-A1 | HYDROPHILIC CURABLE COMPOSITIONS | MITSUI CHEMICALS, INC. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180030230-A1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | MITSUI CHEMICALS, INC. (JP) | 2018-02-01 | — | — | US | disclosed |
| EP-3263635-A1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | Mitsui Chemicals, Inc. (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-3081578-A1 | COMPOSITION FOR HYDROPHILIC CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2016-10-19 | — | — | EP | disclosed |
| CN-105814092-A | Composition for hydrophilic cured product | 三井化学株式会社 | 2016-07-27 | — | — | CN | disclosed |