Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18139366 | 0.90 | THRA (0.41) | TSHRNPSR1RECQLKDM4EMEN1 | |
| SCHEMBL18141022 | 0.90 | KMT2A (0.40) | TSHRL3MBTL1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL28245082 | 0.89 | KMT2A (0.39) | TSHRL3MBTL1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL18139772 | 0.88 | THRA (0.48) | TSHRRECQLKDM4EMEN1KMT2A | |
| SCHEMBL18140065 | 0.86 | THRA (0.55) | RECQLTHRATHRB | |
| SCHEMBL18140521 | 0.86 | THRA (0.55) | RECQLTHRATHRB | |
| SCHEMBL18140410 | 0.86 | THRA (0.55) | RECQLTHRATHRB | |
| SCHEMBL18140483 | 0.86 | THRA (0.55) | RECQLTHRATHRB | |
| SCHEMBL18139152 | 0.86 | THRA (0.55) | RECQLTHRATHRB | |
| SCHEMBL18140328 | 0.86 | THRA (0.55) | RECQLTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180163056-A1 | HYDROPHILIC CURABLE COMPOSITIONS | MITSUI CHEMICALS, INC. (JP) | 2018-06-14 | — | — | US | disclosed |
| EP-3081578-A1 | COMPOSITION FOR HYDROPHILIC CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2016-10-19 | — | — | EP | disclosed |