SCHEMBL18142137

SCHEMBL18142137

CC(C)(C)c1ccc2c(c1)-c1cc(C(C)(C)C)cc([Zr](C3=CC=CC3)=C(c3cccc(C(F)(F)F)c3)c3cccc(C(F)(F)F)c3)c1C2

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.33
CES2 O00748 1/20 0.33
TP53 P04637 1/20 0.31
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16531832 0.99 ACHE (0.32) ACHECES2TP53HDAC11HDAC8
SCHEMBL4427084 0.97 TP53 (0.32) ACHECES2TP53
SCHEMBL3833187 0.91 ACHE (0.30) ACHE
SCHEMBL4497634 0.91
SCHEMBL21406978 0.90 CNR2 (0.31)
Hydrochloric Acid SCHEMBL20994363 0.90
Hydrochloric Acid SCHEMBL16531813 0.90
SCHEMBL20721344 0.89 KCNK3 (0.32)
SCHEMBL2801652 0.88
SCHEMBL20721338 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492471-B2 Polypropylene resin composition and monolayer and multilayer film MITSUI CHEMICALS, INC. (JP) 2022-11-08 US disclosed
US-20200230910-A1 LAMINATE MITSUI CHEMICALS, INC. (JP) 2020-07-23 US disclosed
US-20190300688-A1 POLYPROPYLENE RESIN COMPOSITION AND MONOLAYER AND MULTILAYER FILM MITSUI CHEMICALS, INC. (JP) 2019-10-03 US disclosed
US-20190047264-A1 LAMINATE AND APPLICATION FOR SAME MITSUI CHEMICALS, INC. (JP) 2019-02-14 US disclosed
US-9714306-B2 Olefin resin and method for producing same MITSUI CHEMICALS, INC. (JP) 2017-07-25 US disclosed
US-20170101492-A1 OLEFIN RESIN AND METHOD FOR PRODUCING SAME MITSUI CHEMICALS, INC. (JP) 2017-04-13 US disclosed
EP-2275451-B1 Method for producing propylene-based copolymer MITSUI CHEMICALS INC (JP) 2016-10-19 EP disclosed