Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166002 | 0.83 | KDM4E (0.51) | KDM4ELMNAEPHX1NPC1PKM | |
| SCHEMBL326803 | 0.82 | NQO1 (0.52) | KDM4EEPHX1HTTALDH1A1MTNR1A | |
| SCHEMBL9150083 | 0.81 | KDM4E (0.56) | KDM4ELMNAEPHX1NPC1PKM | |
| SCHEMBL1317147 | 0.81 | CFD (0.61) | KDM4ELMNAEPHX1RAB9AALDH1A1 | |
| SCHEMBL14264240 | 0.81 | HSD17B10 (0.50) | KDM4EAKT1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL3234922 | 0.80 | NQO1 (0.61) | LMNANPC1PKMALDH1A1KMT2A | |
| SCHEMBL15780081 | 0.80 | AKT1 (0.50) | KDM4EAKT1LMNANPC1PKM | |
| SCHEMBL7029122 | 0.80 | KDM4E (0.48) | KDM4ELMNAEPHX1NPC1PKM | |
| SCHEMBL6615190 | 0.79 | KDM4E (0.54) | KDM4ELMNAEPHX1NPC1PKM | |
| SCHEMBL28898703 | 0.78 | KDM4E (0.51) | KDM4EAKT1LMNANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334687-B1 | DIOXA-BICYCLO[3.2.1.]OCTANE-2,3,4-TRIOL DERIVATIVES | PFIZER (US) | 2012-01-04 | — | — | EP | disclosed |
| EP-2334687-A1 | DIOXA-BICYCLO[3.2.1.]OCTANE-2,3,4-TRIOL DERIVATIVES | Pfizer Inc. (US) | 2011-06-22 | — | — | EP | disclosed |