SCHEMBL181479

SCHEMBL181479

c1ccc(C23CC4CC(CC(C4)C2)C3)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.62
GRIN3B O60391 1/20 0.62
GRIN1 Q05586 1/20 0.62
GRIN2A Q12879 1/20 0.62
GRIN2B Q13224 1/20 0.62
GRIN2C Q14957 1/20 0.62
GRIN3A Q8TCU5 1/20 0.62
LMNA P02545 3/20 0.61
ALDH1A1 P00352 2/20 0.61
EPHX2 P34913 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50
NPC1 O15118 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
HSD11B1 P28845 2/20 0.45
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147001 0.90 GRIN2D (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14836389 0.88 GRIN2D (0.51) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2763437 0.87 LMNA (0.77) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL25340712 0.87 LMNA (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL19098015 0.87 LMNA (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1352813 0.86 GRIN2D (0.75) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6890228 0.83 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL27847928 0.83 MEN1 (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4412220 0.82 GRIN2D (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13148543 0.82 LMNA (0.53) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112341933-B Wear-resistant coating and preparation method thereof 青岛豪纳化工科技有限公司 2022-04-05 CN claimed
CN-113122054-A Preparation method of ink and quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
CN-112341933-A Wear-resistant coating and preparation method thereof 张瑞平 2021-02-09 CN claimed
CN-111440042-A Preparation method of 1-phenyladamantane and obtained 1-phenyladamantane 安徽益瑞德新材料科技有限公司 2020-07-24 CN claimed
CN-110970231-A Semi-solid lithium ion capacitor and manufacturing method thereof 上海奥威科技开发有限公司 2020-04-07 CN claimed
CN-105601813-B A kind of modified polyvinyl carbazoles high-molecular luminous material and preparation method thereof 广东工业大学 2017-12-22 CN claimed
CN-105601813-A Modified polyvinyl carbazole high-polymer luminescent material and preparation method thereof UNIV GUANGDONG TECHNOLOGY 2016-05-25 CN claimed
CN-103050295-B A kind of lithium-ion capacitor SHANGHAI AOWEI TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2016-03-23 CN claimed
CN-103050290-B Combining super capacitor device in a kind of SHANGHAI AOWEI TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2016-03-23 CN claimed
US-20140228375-A1 SIGMA RECEPTORS LIGANDS WITH ANTI-APOPTOTIC AND/OR PRO-APOPTOTIC PROPERTIES, OVER CELLULAR MECHANISMS, EXHIBITING PROTOTYPICAL CYTOPROTECTIVE AND ALSO ANTI-CANCER ACTIVITY ANAVEX LIFE SCIENCES CORP. (US) 2014-08-14 US claimed
CN-103887074-A Lithium-ion capacitor long in service life SHANGHAI AOWEI TECHNOLOGY DEV 2014-06-25 CN claimed
CN-103050290-A Internally combined super capacitor SHANGHAI AOWEI TECHNOLOGY DEV 2013-04-17 CN claimed
CN-103050295-A Lithium ion capacitor SHANGHAI AOWEI TECHNOLOGY DEV 2013-04-17 CN claimed
CN-101916878-B Low-temperature organic electrolyte taking gamma-butyrolactone as base solvent and application thereof SHANGHAI AOWEI TECHNOLOGY DEV 2012-12-12 CN claimed
EP-2400965-A1 SIGMA( ) RECEPTORS LIGANDS WITH ANTI-APOPTOTIC AND/OR PRO-APOPTOTIC PROPERTIES, OVER CELLULAR MECHANISMS, EXHIBITING PROTOTYPICAL CYTOPROTECTIVE AND ALSO ANTICANCER ACTIVITY Vamvakides, Alexandre (GR) 2012-01-04 EP claimed
CN-101916878-A Low-temperature organic electrolyte taking gamma-butyrolactone as base solvent and application thereof SHANGHAI AOWEI TECHNOLOGY DEV 2010-12-15 CN claimed
WO-2010097641-A1 SIGMA(σ) RECEPTORS LIGANDS WITH ANTI-APOPTOTIC AND/OR PRO-APOPTOTIC PROPERTIES, OVER CELLULAR MECHANISMS, EXHIBITING PROTOTYPICAL CYTOPROTECTIVE AND ALSO ANTICANCER ACTIVITY VAMVAKIDES ALEXANDRE (GR) 2010-09-02 WO claimed
US-20020137794-A1 Retinoic acid receptor (RAR) agonists, agonists for steroid/thyroid hormone receptor superfamily, and an agonist for a heterodimer partner SALK INSTITUTE FOR BIOLOGICAL STUDIES, THE 2002-09-26 US claimed
US-6436993-B1 SYNERGISTIC MIXTURES OF RETINOIC ACID RECEPTOR (RAR) ANTAGONISTS AND STEROID, THYROID OR RETINOID RECEPTOR AGONISTS SUCH AS PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS USED TO CONTROL CELLULAR PROCESSES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2002-08-20 US claimed
WO-2001003659-A1 USE OF RAR ANTAGONISTS AS MODULATORS OF HORMONE MEDIATED PROCESSES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2001-01-18 WO claimed