SCHEMBL18152597

SCHEMBL18152597

[2H]C([2H])(O)C([2H])([2H])C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10189193 0.65
SCHEMBL17549565 0.65
SCHEMBL1673094 0.62
SCHEMBL20767 0.62
Water SCHEMBL9879556 0.62 ALDH1A1 (0.42)
Water SCHEMBL30060781 0.62
Ethylene Glycol SCHEMBL2307225 0.61
Monoethanolamine SCHEMBL1330822 0.59
Ammonia Solution, Strong SCHEMBL995681 0.59
Hydrochloric Acid SCHEMBL9393760 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016168553-A1 DEUTERATED OBETICHOLIC ACID CONCERT PHARMACEUTICALS, INC. (US) 2016-10-20 WO disclosed