SCHEMBL18152610

SCHEMBL18152610

COc1ccc(C(=O)Nc2ccn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(=O)n2)cc1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 5/20 0.57
P2RY14 Q15391 2/20 0.57
NT5E P21589 1/20 0.57
LMNA P02545 1/20 0.54
THRB P10828 1/20 0.54
MTOR P42345 1/20 0.54
MDM2 Q00987 1/20 0.54
NCOA1 Q15788 1/20 0.54
NCOA3 Q9Y6Q9 1/20 0.54
POLB P06746 1/20 0.51
P2RY2 P41231 3/20 0.50
P2RY4 P51582 3/20 0.50
ABL1 P00519 1/20 0.48
RIN1 Q13671 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25474818 0.87 LMNA (0.53) P2RY6LMNATHRBMTORMDM2
SCHEMBL9128244 0.87 P2RY6 (0.56) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL9128249 0.87 P2RY6 (0.56) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL18852530 0.87 P2RY6 (0.70) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL7267465 0.87 P2RY6 (0.70) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL27878674 0.87 P2RY6 (0.70) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL14853856 0.87 P2RY6 (0.70) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL16805383 0.87 P2RY6 (0.70) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL565905 0.87 P2RY6 (0.70) P2RY6P2RY14NT5ELMNATHRB
SCHEMBL565904 0.87 P2RY6 (0.70) P2RY6P2RY14NT5ELMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 US disclosed
US-20200232005-A1 Methods of Producing and Using Single-Stranded Deoxyribonucleic Acids and Compositions for Use in Practicing the Same TAKARA BIO USA, INC. 2020-07-23 US disclosed
US-10584363-B2 Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same TAKARA BIO USA, INC. (US) 2020-03-10 US disclosed
US-20180100181-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-12 US disclosed
EP-3283638-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2018-02-21 EP disclosed
US-20170349927-A1 METHODS OF PRODUCING AND USING SINGLE-STRANDED DEOXYRIBONUCLEIC ACIDS AND COMPOSITIONS FOR USE IN PRACTICING THE SAME TAKARA BIO USA, INC. 2017-12-07 US disclosed
WO-2016168711-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-10-20 WO disclosed