Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.64 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.50 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152902 | 0.81 | BRD4 (0.57) | BRD4BRD9BRD7BRDT | |
| SCHEMBL29848735 | 0.78 | BRD4 (1.00) | BRD4BRD9BRD7 | |
| SCHEMBL16651293 | 0.78 | BRD4 (1.00) | BRD4BRD9BRD7 | |
| SCHEMBL6334276 | 0.70 | BRD4 (1.00) | BRD4BRD9BRD7BRDT | |
| SCHEMBL14158616 | 0.68 | CYP11B1 (0.39) | BRD4 | |
| SCHEMBL25043198 | 0.68 | BRD4 (0.62) | BRD4BRD9BRD7BRDT | |
| SCHEMBL17029239 | 0.68 | BRD9 (0.77) | BRD4BRD9BRD7BRDT | |
| SCHEMBL19857684 | 0.68 | BRD4 (0.72) | BRD4BRD9BRD7BRDT | |
| SCHEMBL29613205 | 0.68 | BRD4 (0.72) | BRD4BRD9BRD7BRDT | |
| SCHEMBL519320 | 0.68 | NOTUM (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-A2 | BROMODOMAIN INHIBITOR | Celgene Quanticel Research, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168682-A2 | BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-10-20 | — | — | WO | disclosed |