Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154009 | 1.00 | TRPV1 (0.44) | TRPV1EPHX2MAPTL3MBTL1HDAC3 | |
| SCHEMBL20208510 | 0.85 | TRPV1 (0.40) | TRPV1EPHX2MAPTL3MBTL1HDAC3 | |
| SCHEMBL15587040 | 0.82 | HDAC3 (0.44) | TRPV1EPHX2L3MBTL1HDAC3HDAC1 | |
| SCHEMBL18146304 | 0.82 | MAOB (0.46) | EPHX2HDAC3HDAC1HDAC2GRIN2B | |
| SCHEMBL18146306 | 0.82 | MAOB (0.46) | EPHX2HDAC3HDAC1HDAC2GRIN2B | |
| SCHEMBL2092955 | 0.82 | TRPV1 (0.45) | TRPV1EPHX2MAPTL3MBTL1HDAC3 | |
| SCHEMBL17103280 | 0.81 | TRPV1 (0.47) | TRPV1EPHX2MAPTL3MBTL1HDAC3 | |
| SCHEMBL12836091 | 0.80 | NR4A1 (0.63) | TRPV1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL18146421 | 0.80 | NR4A1 (0.63) | TRPV1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL17254288 | 0.79 | HDAC3 (0.46) | TRPV1EPHX2L3MBTL1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow Agrosciences LLC (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168059-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | WO | disclosed |