Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 12/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153984 | 0.87 | MBOAT4 (0.64) | MBOAT4LMNASMN1; SMN2LDHA | |
| SCHEMBL18166101 | 0.76 | MBOAT4 (0.61) | MBOAT4ALDH1A1 | |
| SCHEMBL19971866 | 0.74 | MBOAT4 (0.70) | MBOAT4SMN1; SMN2LDHA | |
| SCHEMBL18166114 | 0.74 | MBOAT4 (0.66) | MBOAT4 | |
| SCHEMBL16699213 | 0.74 | MBOAT4 (0.69) | MBOAT4 | |
| SCHEMBL18166212 | 0.73 | MBOAT4 (0.55) | MBOAT4LMNASMN1; SMN2LDHA | |
| SCHEMBL18166111 | 0.72 | MBOAT4 (0.59) | MBOAT4LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL19971863 | 0.72 | MBOAT4 (0.58) | MBOAT4SMN1; SMN2LDHA | |
| SCHEMBL18166110 | 0.72 | MBOAT4 (0.57) | MBOAT4SMN1; SMN2LDHATHRBALDH1A1 | |
| SCHEMBL19971783 | 0.72 | MBOAT4 (0.53) | MBOAT4SMN1; SMN2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283474-A1 | GHRELIN O-ACYL TRANSFERASE INHIBITORS | Eli Lilly and Company (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168225-A1 | GHRELIN O-ACYL TRANSFERASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2016-10-20 | — | — | WO | disclosed |