Triethylene Glycol

Triethylene Glycol

SCHEMBL1815430

O=C(O)CCC(=O)O.OCCOCCOCCO

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
TSHR P16473 4/20 0.56
MAPK1 P28482 2/20 0.56
LMNA P02545 4/20 0.50
EGLN1 Q9GZT9 3/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
SUCNR1 Q9BXA5 1/20 0.50
CAMK2A Q9UQM7 1/20 0.46
GPR84 Q9NQS5 1/20 0.42
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
PMP22 Q01453 2/20 0.41
BLM P54132 1/20 0.41
HSD17B10 Q99714 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
MAPT P10636 1/20 0.41
SLC15A2 Q16348 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL15049107 1.00 MEN1 (0.61) MEN1KMT2ATSHRMAPK1LMNA
Tetraethylene Glycol SCHEMBL7996654 0.97 MEN1 (0.58) MEN1KMT2ATSHRMAPK1LMNA
Succinic Acid SCHEMBL1986734 0.97 TSHR (0.59) MEN1KMT2ATSHRMAPK1LMNA
Succinic Acid SCHEMBL10943498 0.94 TSHR (0.56) MEN1KMT2ATSHRMAPK1LMNA
SCHEMBL22445005 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1LMNA
SCHEMBL20840356 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1LMNA
SCHEMBL4588453 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1LMNA
SCHEMBL22445115 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1LMNA
Succinic Acid SCHEMBL15048963 0.92 TSHR (0.53) MEN1KMT2ATSHRMAPK1LMNA
SCHEMBL19402669 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043603-A1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-02-08 US claimed
EP-3720896-B1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION LUBRIZOL ADVANCED MAT INC (US) 2023-08-09 EP claimed
EP-4093797-A1 BIODEGRADABLE POLYURETHANE FOAM, BIODEGRADABLE POLYURETHANE FOAM-BASED MATERIAL FOR SACCHARIDE-CLEAVING ENZYME PRODUCTION, METHOD OF SYNTHESIS AND USE THEREOF Ustav makromolekularni chemie AV CR, v.v.i. (CZ) 2022-11-30 EP claimed
US-20210179765-A1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION LUBRIZOL ADVANCED MATERIALS, INC. 2021-06-17 US claimed
EP-3720896-A1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION Lubrizol Advanced Materials, Inc. (US) 2020-10-14 EP claimed
CN-111433249-A Thermoplastic polyurethane with high moisture vapor transmission and low water absorption 路博润先进材料公司 2020-07-17 CN claimed
WO-2019112743-A1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2019-06-13 WO claimed
US-20150259262-A1 COMPOSITIONS USABLE AS FLARE COMPOSITIONS, COUNTERMEASURE DEVICES CONTAINING THE FLARE COMPOSITIONS, AND RELATED METHODS NORTHROP GRUMMAN SYSTEMS CORPORATION 2015-09-17 US claimed
US-4812180-A CROSSLINKED POLYBUTADIENE, LEAD IODIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1989-03-14 US claimed
US-12162974-B2 Thermoplastic polyurethanes with high moisture vapor transmission and low water absorption LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-12-10 US disclosed
US-11920910-B2 Compositions usable as flare compositions, countermeasure devices containing the flare compositions, and related methods NORTHROP GRUMMAN SYSTEMS CORPORATION (US) 2024-03-05 US disclosed
US-20240043603-A1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-02-08 US disclosed
US-11827737-B2 Thermoplastic polyurethanes with high moisture vapor transmission and low water absorption LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-11-28 US disclosed
EP-3720896-B1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION LUBRIZOL ADVANCED MAT INC (US) 2023-08-09 EP disclosed
WO-1995011207-A1 USE OF CARBON FIBRILS TO ENHANCE BURN RATE OF PYROTECHNICS AND GAS GENERANTS THIOKOL CORPORATION (US) 1995-04-27 WO disclosed
WO-1994002435-A1 CASTABLE INFRARED ILLUMINANT COMPOSITIONS THIOKOL CORPORATION (US) 1994-02-03 WO disclosed
WO-1994002436-A1 PRESSABLE INFRARED ILLUMINANT COMPOSITIONS THIOKOL CORPORATION (US) 1994-02-03 WO disclosed
US-4812180-A CROSSLINKED POLYBUTADIENE, LEAD IODIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1989-03-14 US disclosed
US-4812180-A CROSSLINKED POLYBUTADIENE, LEAD IODIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1989-03-14 US disclosed
US-4057442-A Method of disposal of pyrotechnic compositions THIOKOL CORPORATION (US) 1977-11-08 US disclosed