Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573225 | 0.89 | KDM4E (0.63) | KDM4EPKMEPHX1TGFBR1HPGD | |
| SCHEMBL1244714 | 0.85 | KDM4E (0.59) | KDM4EPKMEPHX1TGFBR1HPGD | |
| SCHEMBL584378 | 0.84 | KDM4E (0.54) | KDM4EPKMEPHX1HPGDGLS | |
| SCHEMBL6152939 | 0.84 | KDM4E (0.68) | KDM4EPKMEPHX1TGFBR1HPGD | |
| SCHEMBL381974 | 0.83 | KDM4E (0.53) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL627965 | 0.83 | KDM4E (0.60) | KDM4EPKMEPHX1TGFBR1HPGD | |
| SCHEMBL28063864 | 0.83 | KDM4E (0.53) | KDM4EPKMEPHX1HPGDGLS | |
| SCHEMBL3023628 | 0.82 | KDM4E (0.56) | KDM4EPKMEPHX1TGFBR1HPGD | |
| SCHEMBL1238023 | 0.82 | KDM4E (0.56) | KDM4EPKMEPHX1TGFBR1HPGD | |
| SCHEMBL3581788 | 0.82 | KDM4E (0.56) | KDM4EPKMEPHX1TGFBR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115803030-A | Compounds and methods for KRAS-targeted degradation | 阿维纳斯企业公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2016140878-A9 | PRODRUGS RILUZOLE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-10-20 | — | — | WO | disclosed |