Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | FPR3 | P25089 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | GNRHR | P30968 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755272 | 0.91 | KDM4E (0.58) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL1624331 | 0.91 | KDM4E (0.58) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL1624328 | 0.91 | KDM4E (0.58) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL1245476 | 0.88 | KDM4E (0.64) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL24853346 | 0.88 | KDM4E (0.64) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL5573225 | 0.87 | KDM4E (0.63) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL3632843 | 0.87 | KDM4E (0.63) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL21551436 | 0.87 | KDM4E (0.63) | KDM4EPKMEPHX1SMN1; SMN2HPGD | |
| SCHEMBL21551407 | 0.87 | KDM4E (0.63) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 | |
| SCHEMBL21551109 | 0.86 | KDM4E (0.59) | KDM4EPKMEPHX1TGFBR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549281-A1 | W/O EMULSIONS SPRAYED AS AN AEROSOL | Beiersdorf AG (DE) | 2005-07-06 | — | — | EP | disclosed |
| US-20050143391-A1 | Heterocyclic amides with alpha-4 integrin antagonist activity | J. Uriach Y Compañia S.A. (ES) | 2005-06-30 | — | — | US | disclosed |
| EP-1495044-A1 | HETEROCYCLIC AMIDES WITH ALPHA-4 INTEGRIN ANTAGONIST ACTIVITY | J. Uriach y Compania S.A. (ES) | 2005-01-12 | — | — | EP | disclosed |
| WO-2004030641-A1 | W/O EMULSIONS SPRAYED AS AN AEROSOL | BEIERSDORF AG (DE) | 2004-04-15 | — | — | WO | disclosed |
| WO-2003084984-A1 | HETEROCYCLIC AMIDES WITH ALPHA-4 INTEGRIN ANTAGONIST ACTIVITY | J. URIACH Y COMPANIA S.A. (ES) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143391-A1 | Heterocyclic amides with alpha-4 integrin antagonist activity | ITGB4, ITGA4, ITGA1 | KDM4E 470/4885PKM 3864/4885EPHX1 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.