Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29698933 | 0.90 | DYRK1A (0.67) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18163698 | 0.90 | DYRK1A (0.67) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15271211 | 0.88 | DYRK1A (0.70) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15271105 | 0.87 | TSHR (0.77) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18154435 | 0.87 | HDAC3 (0.73) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19850884 | 0.86 | DYRK1A (0.67) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29699012 | 0.86 | DYRK1A (0.67) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15271273 | 0.86 | DYRK1A (0.73) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15271022 | 0.85 | DYRK1A (0.66) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18154367 | 0.85 | DYRK1A (0.63) | DYRK1AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567438-B | Riluzole prodrugs and uses thereof | 拜尔哈文制药股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| WO-2016140878-A9 | PRODRUGS RILUZOLE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-10-20 | — | — | WO | disclosed |