Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763694 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL18154356 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Hydrogen Peroxide SCHEMBL27858511 | 0.78 | ALDH1A1 (0.54) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL12761588 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Hydrochloric Acid SCHEMBL8844741 | 0.76 | EPHX1 (0.50) | HCAR2TSHREPHX1ACHENAAA | |
| SCHEMBL2725200 | 0.76 | EPHX1 (0.50) | HCAR2TSHREPHX1ACHENAAA | |
| SCHEMBL10042965 | 0.76 | ALDH1A1 (0.40) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL6058509 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL126843 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL17848879 | 0.76 | ALDH1A1 (0.47) | ALDH1A1ATMHCAR2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016140878-A9 | PRODRUGS RILUZOLE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-10-20 | — | — | WO | disclosed |