SCHEMBL18154553

SCHEMBL18154553

O=c1cc(OCc2ccc(F)cc2)ccn1-c1ccc2c(c1)cc1n2CCNCC1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.59
KCNH2 Q12809 2/20 0.51
HRH3 Q9Y5N1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL31573840 0.93 MCHR1 (0.53) MCHR1KCNH2HRH3
SCHEMBL18154557 0.91 MCHR1 (0.59) MCHR1KCNH2
SCHEMBL18154559 0.91 MCHR1 (0.66) MCHR1KCNH2
SCHEMBL18154531 0.90 MCHR1 (0.58) MCHR1KCNH2HRH3
Hydrochloric Acid SCHEMBL18154567 0.90 MCHR1 (0.59) MCHR1KCNH2
SCHEMBL18154581 0.90 MCHR1 (0.54) MCHR1KCNH2
Hydrochloric Acid SCHEMBL18154562 0.90 MCHR1 (0.65) MCHR1KCNH2
Hydrochloric Acid SCHEMBL18154556 0.90 MCHR1 (0.57) MCHR1KCNH2HRH3
Hydrochloric Acid SCHEMBL21981719 0.89 MCHR1 (0.53) MCHR1KCNH2
SCHEMBL18154564 0.88 MCHR1 (0.62) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025094152-A1 18F AND11C RADIOLABELED MCHR1 PET LIGANDS RICHTER GEDEON NYRT. (HU) 2025-05-08 WO disclosed
EP-3286193-A1 INDOLE DERIVATIVES Richter Gedeon Nyrt. (HU) 2018-02-28 EP disclosed
WO-2016166684-A1 INDOLE DERIVATIVES RICHTER GEDEON NYRT. (HU) 2016-10-20 WO disclosed