Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18154556 | 0.99 | MCHR1 (0.57) | MCHR1KCNH2CYP3A4HRH3 | |
| SCHEMBL18154553 | 0.90 | MCHR1 (0.59) | MCHR1KCNH2HRH3 | |
| SCHEMBL18154557 | 0.89 | MCHR1 (0.59) | MCHR1KCNH2 | |
| SCHEMBL18154559 | 0.88 | MCHR1 (0.66) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154581 | 0.88 | MCHR1 (0.54) | MCHR1KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL18154567 | 0.88 | MCHR1 (0.59) | MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL18154562 | 0.88 | MCHR1 (0.65) | MCHR1KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL21981719 | 0.87 | MCHR1 (0.53) | MCHR1KCNH2CYP3A4 | |
| Maleic Acid SCHEMBL31573840 | 0.84 | MCHR1 (0.53) | MCHR1KCNH2CYP3A4HRH3 | |
| SCHEMBL18154551 | 0.84 | MCHR1 (0.51) | MCHR1KCNH2CYP3A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286193-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2020-05-27 | — | — | EP | disclosed |
| US-10329296-B2 | Indole derivatives | RICHTER GEDEON NYRT. (HU) | 2019-06-25 | — | — | US | disclosed |
| US-20180093989-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2018-04-05 | — | — | US | disclosed |
| EP-3286193-A1 | INDOLE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016166684-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329296-B2 | Indole derivatives | TPH1, MCHR1, MC1R | MCHR1 2/4885KCNH2 2003/4885CYP3A4 348/4885 |
| US-20180093989-A1 | INDOLE DERIVATIVES | MC1R, MCHR1, TPH1 | MCHR1 2/4885KCNH2 1806/4885CYP3A4 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.