Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154549 | 0.86 | MCHR1 (0.61) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154520 | 0.84 | MCHR1 (0.67) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154563 | 0.83 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL18154559 | 0.83 | MCHR1 (0.66) | MCHR1KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL18154562 | 0.82 | MCHR1 (0.65) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154554 | 0.80 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL18154524 | 0.80 | MCHR1 (0.50) | MCHR1KCNH2CYP3A4 | |
| Fumaric Acid SCHEMBL18154588 | 0.79 | MCHR1 (0.61) | MCHR1KCNH2CYP3A4 | |
| Maleic Acid SCHEMBL18154587 | 0.79 | MCHR1 (0.61) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL31573845 | 0.78 | MCHR1 (0.56) | MCHR1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286193-A1 | INDOLE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016166684-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-10-20 | — | — | WO | disclosed |