Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.47 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15755676 | 0.83 | GRM4 (0.49) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL4106286 | 0.77 | MAPT (0.65) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL22838167 | 0.77 | TAS2R14 (0.51) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL18884385 | 0.77 | TAS2R14 (0.51) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL14233363 | 0.77 | TAS2R14 (0.51) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL21258954 | 0.75 | TAS2R14 (0.66) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| Hydrochloric Acid SCHEMBL14150624 | 0.75 | TAS2R14 (0.50) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL10652484 | 0.73 | GRM4 (0.55) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL4118632 | 0.73 | MAPT (0.64) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 | |
| SCHEMBL20686490 | 0.73 | TAS2R14 (0.49) | TAS2R14GRM4KCNJ5KCNJ3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283480-A1 | NOVEL ARYL-CYANOGUANIDINE COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016166186-A1 | NOVEL ARYL-CYANOGUANIDINE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-10-20 | — | — | WO | disclosed |