SCHEMBL1815504

SCHEMBL1815504

C=CC(=O)OC(C)Oc1cccc(C(=O)c2ccccc2)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
BCL2 P10415 1/20 0.39
MCL1 Q07820 1/20 0.39
ELANE P08246 1/20 0.39
ABCB1 P08183 5/20 0.38
LMNA P02545 3/20 0.36
CYP3A4 P08684 2/20 0.36
HPGD P15428 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 2/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
CYP2C9 P11712 1/20 0.36
AKR1C3 P42330 1/20 0.36
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28107066 0.90 MAPT (0.56) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL721897 0.90 ELANE (0.46) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL21550263 0.84 ELANE (0.43) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL8989321 0.83 MAPT (0.43) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL22572617 0.82 MAPT (0.45) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL28803942 0.82 MAPT (0.42) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL28230457 0.81 ALDH1A1 (0.40) MAPTKDM4EHSD17B10BCL2MCL1
SCHEMBL28875675 0.81 BCL2 (0.45) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL5498402 0.80 MAPT (0.47) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL1248605 0.80 KDM4E (0.47) MAPTKDM4EHSD17B10LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111201253-B Vinyl chloride-based resin composition and method for preparing the same 韩华思路信(株) 2022-05-24 CN claimed
CN-112654652-A Vinyl chloride-based copolymer and method for preparing the same 韩华思路信(株) 2021-04-13 CN claimed
CN-111201253-A Vinyl chloride-based resin composition and method for preparing the same 韩华思路信(株) 2020-05-26 CN claimed
WO-2012143695-A2 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2012-10-26 WO claimed
EP-2496623-A1 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2012-09-12 EP claimed
EP-2496621-A1 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2012-09-12 EP claimed
EP-2496620-A2 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2012-09-12 EP claimed
WO-2011055108-A1 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2011-05-12 WO claimed
WO-2011055110-A1 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2011-05-12 WO claimed
WO-2011051689-A2 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2011-05-05 WO claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP disclosed
EP-2895894-B1 POLYMERS FOR CONTACT LENSES OCUTEC LTD (GB) 2023-08-23 EP disclosed
CN-111201253-B Vinyl chloride-based resin composition and method for preparing the same 韩华思路信(株) 2022-05-24 CN disclosed
US-20210369911-A1 HYDROGEL COMPOSITIONS UNIVERSITÉ DE HAUTE-ALSACE (FR) 2021-12-02 US disclosed
US-11168177-B2 Polyurethanes for contact lenses OCUTEC LIMITED (GB) 2021-11-09 US disclosed
WO-2012056195-A2 POLYMER FOR CONTACT LENSES OCUTEC LIMITED (GB) 2012-05-03 WO disclosed
WO-2011055110-A1 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2011-05-12 WO disclosed
WO-2011055108-A1 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2011-05-12 WO disclosed
WO-2011051689-A2 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2011-05-05 WO disclosed
WO-2011051690-A2 POLYMERS FOR CONTACT LENSES OCUTEC LIMITED (GB) 2011-05-05 WO disclosed