Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 2/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.57 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NMT1 | P30419 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18155074 | 1.00 | LPAR2 (0.59) | LPAR2LPAR1KMT2AMEN1CREBBP | |
| SCHEMBL16269020 | 0.96 | LPAR2 (0.65) | LPAR2LPAR1KMT2AMEN1CREBBP | |
| SCHEMBL19911214 | 0.88 | PARP1 (0.54) | LPAR2LPAR1KMT2AMEN1CREBBP | |
| SCHEMBL19911213 | 0.88 | LPAR2 (0.56) | LPAR2LPAR1KMT2AMEN1CREBBP | |
| SCHEMBL15798246 | 0.82 | CREBBP (0.79) | LPAR2LPAR1KMT2AMEN1CREBBP | |
| SCHEMBL9364431 | 0.82 | CREBBP (0.79) | LPAR2LPAR1KMT2AMEN1CREBBP | |
| SCHEMBL9364423 | 0.82 | CREBBP (0.79) | LPAR2LPAR1KMT2AMEN1CREBBP | |
| SCHEMBL7858424 | 0.81 | LPAR2 (0.72) | LPAR2LPAR1KMT2AMEN1LPAR3 | |
| SCHEMBL7858420 | 0.81 | LPAR2 (0.72) | LPAR2LPAR1KMT2AMEN1LPAR3 | |
| SCHEMBL17239834 | 0.79 | MEN1 (0.61) | LPAR2LPAR1KMT2AMEN1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562920-B2 | Ln(III) and Ga(III) metallacrown complexes | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-02-18 | — | — | US | disclosed |
| US-20180127438-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | NATIONAL SCIENCE FOUNDATION | 2018-05-10 | — | — | US | disclosed |
| EP-3283497-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | The Regents of The University of Michigan (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016166380-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127438-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | NEU3, GALNT3, LGALS3 | LPAR2 604/4885LPAR1 451/4885KMT2A 2081/4885 |
| US-10562920-B2 | Ln(III) and Ga(III) metallacrown complexes | NEU3, GALNT3, LGALS3 | LPAR2 604/4885LPAR1 451/4885KMT2A 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.