Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751312 | 0.84 | GLS (0.62) | GLSKDM4EALDH1A1LMNAGLA | |
| SCHEMBL13006677 | 0.82 | GLS (0.60) | GLSKDM4EALDH1A1LMNAGLA | |
| SCHEMBL17489160 | 0.81 | GLS (0.75) | GLSKDM4EALDH1A1LMNAGLA | |
| SCHEMBL18141977 | 0.80 | KDM4E (0.61) | GLSKDM4EALDH1A1LMNAPKM | |
| SCHEMBL10293302 | 0.79 | GLS (0.56) | GLSKDM4EALDH1A1LMNAGLA | |
| SCHEMBL16254580 | 0.79 | KDM4E (0.55) | GLSKDM4EALDH1A1LMNAPKM | |
| SCHEMBL22267957 | 0.78 | GLS (0.55) | GLSKDM4EALDH1A1LMNAGLA | |
| SCHEMBL621968 | 0.78 | GLS (0.64) | GLSKDM4EALDH1A1LMNAGLA | |
| SCHEMBL10310266 | 0.78 | GLS (0.50) | GLSKDM4EALDH1A1LMNAGLA | |
| SCHEMBL18157878 | 0.77 | GLS (0.69) | GLSKDM4EALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895482-B1 | HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2016-10-19 | — | — | EP | disclosed |