Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18155974 | 0.85 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL18155972 | 0.84 | CYP3A4 (0.45) | CYP3A4 | |
| SCHEMBL15685815 | 0.84 | CYP3A4 (0.45) | CYP3A4 | |
| SCHEMBL15685794 | 0.82 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL13829957 | 0.82 | CYP3A4 (0.43) | CYP3A4 | |
| SCHEMBL14914521 | 0.82 | CYP3A4 (0.43) | CYP3A4 | |
| SCHEMBL7925281 | 0.80 | ADRB3 (0.33) | — | |
| SCHEMBL13830431 | 0.78 | GAA (0.32) | CYP3A4 | |
| SCHEMBL18156074 | 0.76 | ALOX15 (0.31) | — | |
| SCHEMBL14377836 | 0.76 | ADRB3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2909205-B1 | 9-METHYL SUBSTITUTED HEXADECAHYDROCYCLOPROPA(E)PYRROLO(1,2-A)(1,4)DIAZACYCLOPENTADECINYL CARBAMATE DERIVATIVES AS NON-STRUCTURAL 3 (NS3) PROTEASE INHIBITORS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS | BRISTOL MYERS SQUIBB CO (US) | 2016-11-23 | — | — | EP | disclosed |
| EP-2705049-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-10-19 | — | — | EP | disclosed |