Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18182642 | 0.94 | PTGER1 (0.38) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL18182262 | 0.92 | NPC1 (0.38) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL18182000 | 0.92 | MAPK14 (0.38) | PTGER1PTGER4PTGER3PTGER2MRGPRX4 | |
| SCHEMBL18178729 | 0.88 | MRGPRX4 (0.38) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL18178662 | 0.87 | MRGPRX4 (0.37) | PTGER1PTGER4PTGER3PTGER2MRGPRX4 | |
| SCHEMBL18182578 | 0.87 | MRGPRX4 (0.37) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL18532764 | 0.87 | MRGPRX4 (0.39) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL18182990 | 0.86 | HSP90AA1 (0.44) | NPC1KMT2ATP53HPGDRAB9A | |
| SCHEMBL18156248 | 0.85 | SLC22A12 (0.37) | NPC1FABP4FABP5MRGPRX4KMT2A | |
| SCHEMBL18156319 | 0.85 | MRGPRX4 (0.38) | PTGER1PTGER4PTGER3PTGER2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081559-A1 | AROMATIC COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Limited (JP) | 2016-10-19 | — | — | EP | disclosed |