Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18156404 | 0.91 | MRGPRX4 (0.45) | MRGPRX4RXRARXRBRXRGS1PR1 | |
| SCHEMBL18156260 | 0.90 | MRGPRX4 (0.44) | MRGPRX4RXRARXRBRXRGALOX15 | |
| SCHEMBL18156264 | 0.89 | MRGPRX4 (0.43) | MRGPRX4RXRARXRBRXRGALOX15 | |
| SCHEMBL18156351 | 0.88 | MRGPRX4 (0.43) | MRGPRX4RXRARXRBRXRGALOX15 | |
| SCHEMBL18182012 | 0.88 | MRGPRX4 (0.44) | MRGPRX4RXRARXRBRXRGALOX15 | |
| SCHEMBL18181983 | 0.88 | RXRA (0.47) | MRGPRX4RXRARXRBRXRGALOX15 | |
| SCHEMBL18182569 | 0.88 | MRGPRX4 (0.45) | MRGPRX4RXRARXRBRXRGALOX15 | |
| SCHEMBL18182546 | 0.88 | CYP1A2 (0.41) | MRGPRX4RXRARXRBRXRGFFAR4 | |
| SCHEMBL18156348 | 0.88 | MRGPRX4 (0.42) | MRGPRX4RXRARXRBRXRGALOX15 | |
| SCHEMBL18182570 | 0.88 | MRGPRX4 (0.46) | MRGPRX4RXRARXRBRXRGALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081559-A1 | AROMATIC COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Limited (JP) | 2016-10-19 | — | — | EP | disclosed |