Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 4/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18182605 | 0.92 | TP53 (0.46) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18532839 | 0.90 | PTGDR2 (0.48) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18530979 | 0.90 | PTGDR2 (0.46) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18182577 | 0.89 | ALDH1A1 (0.43) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18156101 | 0.89 | HTT (0.43) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18182866 | 0.89 | TP53 (0.45) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18183063 | 0.88 | MRGPRX4 (0.41) | TP53HTTMRGPRX4FABP4FABP5 | |
| SCHEMBL18182450 | 0.87 | TP53 (0.41) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18182602 | 0.86 | MRGPRX4 (0.45) | TP53HTTMRGPRX4PTGDR2FABP4 | |
| SCHEMBL18182890 | 0.86 | PTGDR2 (0.43) | PTGDR2NPC1FFAR1FFAR4LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| EP-3081559-A1 | AROMATIC COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Limited (JP) | 2016-10-19 | — | — | EP | disclosed |