Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 19/20 | 0.63 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138588 | 0.86 | LCAT (0.79) | LCAT | |
| SCHEMBL18138592 | 0.86 | LCAT (0.79) | LCAT | |
| SCHEMBL18138585 | 0.86 | LCAT (0.79) | LCAT | |
| SCHEMBL16948831 | 0.78 | LCAT (0.56) | LCAT | |
| SCHEMBL16948816 | 0.77 | LCAT (0.56) | LCAT | |
| SCHEMBL18138602 | 0.77 | LCAT (0.65) | LCAT | |
| SCHEMBL18138607 | 0.77 | LCAT (0.65) | LCAT | |
| SCHEMBL18138606 | 0.77 | LCAT (0.65) | LCAT | |
| SCHEMBL16948785 | 0.76 | LCAT (0.51) | LCAT | |
| SCHEMBL16948620 | 0.75 | LCAT (0.56) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081566-A1 | 5-HYDROXY-4-(TRIFLUOROMETHYL)PYRAZOLOPYRIDINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2016-10-19 | — | — | EP | disclosed |