Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12093446 | 1.00 | GCK (0.46) | GCKGCKR | |
| SCHEMBL33228 | 1.00 | GCK (0.46) | GCKGCKR | |
| SCHEMBL18156 | 0.92 | GCK (0.44) | GCKGCKR | |
| SCHEMBL17169 | 0.92 | GCK (0.44) | GCKGCKR | |
| SCHEMBL12093443 | 0.92 | GCK (0.44) | GCKGCKR | |
| SCHEMBL12089443 | 0.92 | GCK (0.45) | GCKGCKR | |
| SCHEMBL12089688 | 0.92 | GCK (0.45) | GCKGCKR | |
| SCHEMBL12093442 | 0.89 | GCK (0.46) | GCKGCKR | |
| SCHEMBL18415 | 0.89 | GCK (0.46) | GCKGCKR | |
| SCHEMBL18389 | 0.89 | GCK (0.46) | GCKGCKR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |